BENZODIAZEPINE EQUIVALENCE TABLE

 

enzodiazepines1	Half-life (hrs)2 [active metabolite]	Approximately Equivalent Oral dosages (mg)3	Market Aim4
Alprazolam (Xanax, Xanor, Tafil)	6-12	0.5	a
Bromazepam (Lexotan, Lexomil)	10-20	5-6	a
Chlordiazepoxide (Librium)	5-30 [36-200]	25	a
Clobazam (Frisium)5	12-60	20	a,e
Clonazepam (Klonopin, Rivotril)5	18-50	0.5	a,e
Clorazepate (Tranxene)	[36-200]	15	a
Diazepam (Valium)	20-100 [36-200]	10	a
Estazolam (ProSom, Nuctalon)	10-24	1-2	h
Flunitrazepam (Rohypnol)	18-26 [36-200]	1	h
Flurazepam (Dalmane)	[40-250]	15-30	h
Halazepam (Paxipam)	[30-100]	20	a
Ketazolam (Anxon)	30-100 [36-200]	15-30	a
Loprazolam (Dormonoct)	6-12	1-2	h
Lorazepam (Ativan, Temesta, Tavor)	10-20	1	a
Lormetazepam (Noctamid)	10-12	1-2	h
Medazepam (Nobrium)	36-200	10	a
Nitrazepam (Mogadon)	15-38	10	h
Nordazepam (Nordaz, Calmday)	36-200	10	a
Oxazepam (Serax, Serenid, Serepax, Seresta)	4-15	20	a
Prazepam (Centrax, Lysanxia)	[36-200]	10-20	a
Quazepam (Doral)	25-100	20	h
Temazepam (Restoril, Normison, Euhypnos)	8-22	20	h
Triazolam (Halcion)	2	0.5	h
Non-benzodiazepines with similar effects 1, 6
Zaleplon (Sonata)	2	20	h
Zolpidem (Ambien, Stilnoct, Stilnox)	2	20	h
Zopiclone (Zimovane, Imovane)	5-6	15	h
Eszopiclone (Lunesta)	6 (9 in elderly)	3	h